“We think that is quite likely,” prosecutor Hagan Scotten told the judge when asked if the feds planned to file what’s known as a “superseding indictment” in the case.

The prosecutor said it’s “likely additional defendants will be charged” and that it’s “possible” that the new indictment would include more charges against the mayor.

The bombshell development came soon after Hizzoner gave a thumbs-up as he was heckled while making his way to the Lower Manhattan courthouse for the procedural hearing before Judge Dale Ho.

“Resign! The whole administration,” one man raged. “Criminal. You’re a criminal. You’re a sellout. Resign, sucker.”

The hearing marks the first time Adams has appeared in court since he pleaded not guilty to conspiracy, wire fraud and bribery charges at his historic arraignment last Friday.

Adams, who is the first sitting New York City mayor to be criminally indicted, is accused of taking improper gifts from Turkish officials and businesspeople — including $123,000 in free, or heavily discounted, hotels and flights — dating back to his time as the Brooklyn borough president a decade ago.

He also fraudulently obtained $10 million in public campaign funds, federal prosecutors alleged in the five-count indictment.

In exchange for the alleged freebies, Adams coughed up favors — including pressuring city officials to push through speedy approvals for the Turkish Consulate in Manhattan, the court papers charge.

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