An Upper East Side kosher restaurant was targeted by vandals early Wednesday.

Rothschild TLV on Lexington Avenue had its front window smashed overnight — leaving a gaping hole, images posted on X show.

The upscale eatery is inspired by Rothschild Boulevard in Tel Aviv, according to the restaurant’s website.

The NYPD did not immediately respond to a request for information from The Post.

The Big Apple has been plagued by a spike in antisemitism in the wake of the Oct. 7 sneak attack on Israel by Hamas and the subsequent Israeli offensive in the Gaza Strip.