A 61-year-old Queens woman was shot dead Friday night and her son charged with her murder, police said.

Natalie Coggins was shot once in the head at around 9:25 p.m. inside her home at 160-46 121st Avenue in Jamaica, police said.

EMS pronounced her dead at the scene.

Dashawn Coggins, 36, was arrested and charged with murder and criminal possession of a weapon, authorities said.

Police did not say what led to the deadly shooting.

“The investigation remains ongoing,” the NYPD said.

In Chinatown, a 62-year-old man was hospitalized Friday night after two thugs punched him in the back of the head on Eldridge Street, near Hester Street, cops said.

EMS transported the victim to Bellevue Hospital in stable condition following the 8:15 p.m. assault.

There were no arrests.

Police described the suspects as a 25-year-old man with a light complexion and blonde hair and a man in his 20s with a dark complexion.

The incident follows a spate of sucker-punch attacks citywide, but cops don’t yet know if this is another. “We don’t know if it’s a random attack.

These guys could have had words,” an NYPD spokesman said.

Blood was also shed in Brooklyn late Friday night when a man was stabbed in the torso at the Cypress Hills Houses on Sutter Avenue, cops said.

These guys could have had words,” an NYPD spokesman said.

The “uncooperative” victim was taken to Brookdale Hospital in stable condition following the 11:40 p.m. incident.

There were no arrests.

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